Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544423 | 0.86 | SMO (0.43) | NOTUMP2RX7NPC1RAB9AMEN1 | |
| SCHEMBL6532686 | 0.84 | NPBWR1 (0.54) | NOTUMP2RX7NPC1RAB9ADRD2 | |
| SCHEMBL1416762 | 0.83 | P2RX7 (0.52) | CCR1P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL31636507 | 0.83 | NOTUM (0.45) | NOTUMCCR1P2RX7NPC1RAB9A | |
| SCHEMBL1568047 | 0.83 | SMO (0.57) | P2RX7NPC1RAB9ADRD2DRD4 | |
| SCHEMBL26387445 | 0.77 | GRM1 (0.45) | NOTUMCCR1NPC1RAB9AMEN1 | |
| SCHEMBL26136378 | 0.76 | P2RX7 (0.47) | NOTUMCCR1P2RX7NPC1RAB9A | |
| SCHEMBL31636797 | 0.76 | KMT2A (0.53) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5021185 | 0.74 | NPC1 (0.45) | NOTUMCCR1NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL16245892 | 0.72 | NPC1 (0.44) | NOTUMCCR1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014181287-A1 | HETEROCYCLYL COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2014-11-13 | — | — | WO | disclosed |
| US-5990139-A | 2,5-DIOXO-4-(PYRIDYL OR PHENYL-(N-HETEROCYCLE(C4N,C3N2))-ALKYLENOXY-(1,4-PHENYLENE) -)THIADIAZOLIDINES; ANTIDIABETIC AND -LIPEMIC AGENTS; SIDE EFFECT REDUCTION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |