Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272305 | 0.82 | KMT2A (0.53) | ALDH1A1MAPTGAAGRM2KMT2A | |
| SCHEMBL6269771 | 0.81 | KMT2A (0.56) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL12974281 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL8115869 | 0.78 | GRM2 (0.74) | GRM2 | |
| SCHEMBL6267118 | 0.77 | NPC1 (0.59) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL6269927 | 0.77 | LMNA (0.54) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL8471969 | 0.77 | LMNA (0.46) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL6269176 | 0.76 | KMT2A (0.51) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL6267128 | 0.76 | LMNA (0.48) | ALDH1A1MAPTGAAKMT2ALMNA | |
| SCHEMBL6267126 | 0.76 | LMNA (0.48) | ALDH1A1MAPTGAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990139-A | 2,5-DIOXO-4-(PYRIDYL OR PHENYL-(N-HETEROCYCLE(C4N,C3N2))-ALKYLENOXY-(1,4-PHENYLENE) -)THIADIAZOLIDINES; ANTIDIABETIC AND -LIPEMIC AGENTS; SIDE EFFECT REDUCTION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |