Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL16369836 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL5817385 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL126063 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL8192019 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL10019370 | 0.78 | — | — | |
| SCHEMBL16920532 | 0.78 | — | — | |
| SCHEMBL1235355 | 0.78 | — | — | |
| SCHEMBL22228591 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL16133408 | 0.75 | OR51E2 (0.32) | OR51E2SLC22A6GRIK1 | |
| SCHEMBL10044872 | 0.75 | TET2 (0.41) | TET2TET3OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876916-A | ADMINISTRATION OF GLYCEROL-PYRUVATE OR HYDROXYACETONE PYRUVATE ESTER WITH BIOCOMPATIBLE CARRIER TO MAMMALS; AS HIGH CALORIE FOOD, ANTICHOLESTEROL AGENTS, ANTIISHEMIC AGENTS, ORGAN PRESERVATIVE, ANTIDIABETIC AGENTS | CASE WESTERN RESERVE UNIVERSITY (US) | 1999-03-02 | — | — | US | claimed |
| EP-0888267-A1 | NOVEL PYRUVATE COMPOUNDS AND METHODS FOR USE THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034856-A1 | NOVEL PYRUVATE COMPOUNDS AND METHODS FOR USE THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 1997-09-25 | — | — | WO | claimed |