SCHEMBL126063

SCHEMBL126063

O=C(O)C(=O)CC(O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.60
TET2 Q6N021 6/20 0.56
TET3 O43151 2/20 0.56
TET1 Q8NFU7 1/20 0.56
OR51E2 Q9H255 2/20 0.48
KDM4A O75164 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
KDM2A Q9Y2K7 2/20 0.42
CA4 P22748 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.36
GPR84 Q9NQS5 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8192019 1.00 SMN1; SMN2 (0.60) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL5817385 1.00 SMN1; SMN2 (0.60) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL22228591 0.97 SMN1; SMN2 (0.57) SMN1; SMN2TET2TET3TET1OR51E2
Pyruvate SCHEMBL16369836 0.90 SMN1; SMN2 (0.50) SMN1; SMN2TET2TET3TET1OR51E2
Glyoxylate SCHEMBL1130730 0.88 SMN1; SMN2 (0.48) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL8470732 0.78 SMN1; SMN2 (0.36) SMN1; SMN2TET2TET3TET1OR51E2
Oxaloacetate SCHEMBL2048613 0.78 SMN1; SMN2 (0.68) SMN1; SMN2TET2TET3TET1OR51E2
Malic Acid SCHEMBL6863763 0.77 SMN1; SMN2 (0.88) SMN1; SMN2TET2TET3TET1OR51E2
Malic Acid SCHEMBL28319573 0.77 SMN1; SMN2 (0.88) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL1533908 0.76 OR51E2 (0.46) SMN1; SMN2TET2TET3TET1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710813-B Microorganism and method for producing glycolic acid and glycine by reverse glyoxylate arms 布拉斯科公司 2025-05-30 CN claimed
EP-4558605-A1 RECOMBINANT METHYLOTROPHIC MICROORGANISM ETH Zurich (CH) 2025-05-28 EP claimed
EP-4537111-A2 MULTI-OMICS ASSESSMENT Prognomiq Inc (US) 2025-04-16 EP claimed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
US-20240318208-A1 NOVEL METHOD FOR PRODUCING POLY-4-HYDROXYBUTYRATE AND 1,4-BUTANEDIOL CJ CHEILJEDANG CORPORATION (KR) 2024-09-26 US claimed
CN-117916385-A Novel process for the production of poly-4-hydroxybutyrate and 1, 4-butanediol CJ第一制糖株式会社 2024-04-19 CN claimed
EP-4349994-A1 NOVEL METHOD FOR PRODUCING POLY-4-HYDROXYBUTYRATE AND 1,4-BUTANEDIOL CJ Cheiljedang Corporation (KR) 2024-04-10 EP claimed
WO-2024018304-A1 RECOMBINANT METHYLOTROPHIC MICROORGANISM ETH ZURICH (CH) 2024-01-25 WO claimed
EP-4310174-A1 RECOMBINANT METHYLOTROPHIC MICROORGANISM ETH Zurich (CH) 2024-01-24 EP claimed
EP-0692539-B1 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO KK (JP) 1999-09-22 EP claimed
CN-1214366-A Method for producing optically active compounds KYOWA HAKKO KOGYO KK (JP) 1999-04-21 CN claimed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 EP claimed
US-5643769-A Process for producing an optically active γ-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-07-01 US claimed
EP-0555475-B1 PROCESS FOR PRODUCING 4-HYDROXY-L-PROLINE KYOWA HAKKO KOGYO KK (JP) 1997-05-14 EP claimed
US-5607848-A MIXING GLYOXYLIC ACID, PYRUVIC ACID, MICROORGANISM KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-03-04 US claimed
EP-0692539-A2 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-01-17 EP claimed
EP-0670371-A2 Process for producing optically active 4-hydroxy-2-ketoglutaric acids KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-09-06 EP claimed
US-5374542-A Converting 4-hydroxy-2-oxoglutaric in aqueous medium in presence of amino gropu donor and enzyme source KYOWA HAKKO KOGYO CO., LTD. (JP) 1994-12-20 US claimed
EP-0555475-A1 PROCESS FOR PRODUCING 4-HYDROXY-L-PROLINE KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-08-18 EP claimed