Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 1.00 |
| ▸ | DRD3 | P35462 | 16/20 | 1.00 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470731 | 1.00 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL4483845 | 0.78 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL9773137 | 0.78 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL8470807 | 0.78 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL8470805 | 0.78 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL4483728 | 0.77 | DRD2 (0.62) | DRD2DRD3DRD4 | |
| SCHEMBL9203036 | 0.77 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL9199501 | 0.77 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL9206102 | 0.77 | DRD2 (0.67) | DRD2DRD3 | |
| SCHEMBL8473280 | 0.77 | DRD2 (1.00) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977110-A | Substituted cyclohexylamines as central nervous systems agents | WARNER-LAMBERT COMPANY (US) | 1999-11-02 | — | — | US | disclosed |