Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379464 | 0.87 | HDAC3 (0.31) | MEN1GAAKMT2AHDAC1HDAC2 | |
| SCHEMBL7854835 | 0.84 | MEN1 (0.39) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL4287818 | 0.80 | CA2 (0.52) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL4287823 | 0.80 | CA2 (0.52) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL8470935 | 0.77 | FOLH1 (0.36) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL17079748 | 0.75 | MEN1 (0.49) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL8208751 | 0.75 | FOLH1 (0.50) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL23363788 | 0.75 | MEN1 (0.42) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL4269623 | 0.75 | FOLH1 (0.56) | SLC1A1FOLH1 | |
| SCHEMBL8882482 | 0.74 | GRIK1 (0.49) | MEN1GAAKMT2ASLC1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033847-A1 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | disclosed |