Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287823 | 1.00 | CA2 (0.52) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL28625289 | 0.88 | CA2 (0.52) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL17079748 | 0.84 | MEN1 (0.49) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL8882482 | 0.83 | GRIK1 (0.49) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL12268130 | 0.81 | CA2 (0.45) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL4755353 | 0.81 | CA2 (0.45) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL8208751 | 0.81 | FOLH1 (0.50) | MEN1GAAKMT2ASLC1A1FOLH1 | |
| SCHEMBL23363788 | 0.80 | MEN1 (0.42) | CA2MEN1GAAKMT2ASLC1A1 | |
| SCHEMBL8470938 | 0.80 | MEN1 (0.41) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL15164249 | 0.80 | MEN1 (0.41) | MEN1GAAKMT2ASLC1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637696-B2 | Methods for preparing amides and amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-31 | — | — | US | disclosed |
| US-8269039-B2 | Amino acids and catalytic preparatory methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | WARF - WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030210-A1 | METHODS FOR PREPARING AMIDES AND AMINO ACIDS | DNPEP, PTMS, QPCT | CA2 2878/4885MAPK1 4782/4885MEN1 3115/4885 |
| US-20090264676-A1 | Amino acids and catalytic preparatory methods | DNPEP, PREP, ENPEP | CA2 2794/4885MAPK1 4540/4885MEN1 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.