SCHEMBL8470964

SCHEMBL8470964

COc1cc2c(c3ccccc13)NCS2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
ALOX15 P16050 1/20 0.36
EP300 Q09472 2/20 0.35
KAT8 Q9H7Z6 1/20 0.35
NQO1 P15559 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
IMPDH2 P12268 1/20 0.33
IMPDH1 P20839 1/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10626190 0.89 NQO1 (0.37) ALOX15NQO1LMNAHPGDSMN1; SMN2
SCHEMBL11817394 0.74 IDO1 (0.36) IDO1ALOX15EP300KAT8NQO1
SCHEMBL11816893 0.70 ALDH1A1 (0.41) EP300HPGDMAPTKDM4ECA1
SCHEMBL10501198 0.69 NOX1 (0.51) IDO1ALOX15LMNAHPGDSMN1; SMN2
SCHEMBL1790645 0.67 ALDH1A1 (0.41) LMNAHPGDMAPTKDM4ECA1
SCHEMBL19999173 0.66 CA12 (0.52) IDO1ALOX15EP300KAT8NQO1
SCHEMBL11820480 0.66 CYP1A2 (0.41) HPGDSMN1; SMN2MAPTKDM4ENISCH
SCHEMBL419307 0.63 IDO1 (0.73) IDO1EP300KAT8NQO1LMNA
SCHEMBL29380721 0.63 IDO1 (0.73) IDO1EP300KAT8NQO1LMNA
SCHEMBL3670609 0.61 SMN1; SMN2 (0.61) IDO1EP300KAT8NQO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed