SCHEMBL8471998

SCHEMBL8471998

CO[Si](CCCN(C)[C@@](C)(CC(=O)O)C(=O)O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
FFAR1 O14842 1/20 0.30
CPT2 P23786 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8472373 0.85 HMGCR (0.32) HMGCRCHRM1TBXA2RADRA1ACYP2D6
SCHEMBL15492621 0.81
SCHEMBL6567151 0.79 FFAR1 (0.32) HMGCRCHRM1TBXA2RADRA1ACYP2D6
SCHEMBL15492616 0.72
SCHEMBL19457979 0.71 FFAR1 (0.31) FFAR1CPT2TDP1
SCHEMBL2490354 0.70 LTA4H (0.39) ADRA1ATSHRCYP2C19TDP1
SCHEMBL196287 0.70
SCHEMBL512341 0.70 BCHE (0.32)
Acetic Acid SCHEMBL1973747 0.70 PAOX (0.34) TSHR
SCHEMBL26669517 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970709-B1 SINGLE-COMPONENT MOISTURE-CURABLE COATINGS BASED ON N-SUBSTITUTED UREA POLYMERS WITH EXTENDED CHAINS AND TERMINAL ALKOXYSILANES US GOV SEC NAVY (US) 2017-10-18 EP claimed
US-5998504-A PROTECTIVE POLYURETHANE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed