SCHEMBL6567151

SCHEMBL6567151

CO[Si](CCC(C)(C)CN(C)[C@@](C)(CC(=O)O)C(=O)O)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.32
CPT2 P23786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8471998 0.79 HMGCR (0.33) FFAR1CPT2TDP1HMGCRCHRM1
SCHEMBL6569057 0.70
SCHEMBL2720535 0.67 CYP2D6 (0.33) FFAR1CPT2TDP1HMGCRCHRM1
SCHEMBL19457979 0.66 FFAR1 (0.31) FFAR1CPT2TDP1
SCHEMBL8472373 0.66 HMGCR (0.32) HMGCRCHRM1TBXA2RADRA1ACYP2D6
SCHEMBL5162755 0.64 FFAR1 (0.34) FFAR1CPT2TDP1HMGCRCHRM1
SCHEMBL15492621 0.63
SCHEMBL8580780 0.63 HMGCR (0.50) FFAR1CPT2TDP1HMGCRCHRM1
SCHEMBL28356329 0.63 NUDT1 (0.31)
SCHEMBL15746927 0.60 LMNA (0.32) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0831108-B1 Curable silane-endcapped compositions having improved performance CROMPTON CORP (US) 2004-04-07 EP disclosed
US-6001946-A Curable silane-encapped compositions having improved performances WITCO CORPORATION (US) 1999-12-14 US disclosed
EP-0831108-A1 Curable silane-endcapped compositions having improved performance OSi Specialties, Inc. (US) 1998-03-25 EP disclosed