Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472109 | 0.81 | MAPT (0.42) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8421439 | 0.79 | PPARG (0.43) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8471742 | 0.79 | MAPT (0.41) | POLBMAPTTHRBGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL8505855 | 0.78 | PPARG (0.44) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8472016 | 0.78 | PDE4A (0.36) | GAAALDH1A1MEN1KMT2APDE4A | |
| SCHEMBL9545693 | 0.77 | MAPT (0.42) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL6032173 | 0.77 | MAPT (0.54) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8659796 | 0.76 | MAPT (0.43) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8333731 | 0.75 | PPARG (0.46) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL3774754 | 0.75 | MAPT (0.50) | POLBMAPTTHRBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952356-A | TREATING DIABETES IN A MAMMAL WITH AN ACTIVE MATERIAL AND A GLUCOSIDASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |