Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774754 | 0.78 | MAPT (0.50) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL8472109 | 0.76 | MAPT (0.42) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL8472017 | 0.76 | POLB (0.45) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL8421439 | 0.76 | PPARG (0.43) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL8471742 | 0.75 | MAPT (0.41) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL6032173 | 0.75 | MAPT (0.54) | MAPTTHRBGAAPOLBTP53 | |
| Hydrochloric Acid SCHEMBL8505855 | 0.75 | PPARG (0.44) | MAPTTHRBGAAPOLBTP53 | |
| SCHEMBL8440670 | 0.73 | PPARG (0.46) | KDM4ECYP2C9PPARG | |
| SCHEMBL8659791 | 0.72 | MAPT (0.44) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7469304 | 0.72 | POLB (0.55) | MAPTTHRBGAAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824694-A | Thiazolidine derivatives for the treatment of psoriasis | BETHESDA PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |