Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472027 | 0.97 | L3MBTL1 (0.47) | L3MBTL1KDM4ELMNACNR2ALDH1A1 | |
| SCHEMBL8477130 | 0.87 | KMT2A (0.55) | L3MBTL1KDM4ELMNACNR2ALDH1A1 | |
| SCHEMBL8476027 | 0.86 | KMT2A (0.52) | L3MBTL1KDM4ELMNACNR2ALDH1A1 | |
| SCHEMBL8474648 | 0.85 | PTGER4 (0.48) | L3MBTL1KDM4ELMNACNR2ALDH1A1 | |
| SCHEMBL8477133 | 0.85 | PTGER4 (0.48) | KDM4ELMNACNR2ALDH1A1SCARB1 | |
| SCHEMBL8476486 | 0.85 | PTGER4 (0.50) | L3MBTL1KDM4ELMNAALDH1A1HTT | |
| SCHEMBL8476904 | 0.85 | KDM4E (0.43) | L3MBTL1KDM4ELMNACNR2ALDH1A1 | |
| SCHEMBL8473765 | 0.84 | PTGER4 (0.52) | KDM4ECNR2ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8472573 | 0.83 | KMT2A (0.44) | KMT2AMEN1PTGER4 | |
| SCHEMBL8475515 | 0.83 | PTGER4 (0.51) | KDM4ELMNACNR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |