Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476486 | 0.85 | PTGER4 (0.50) | KDM4EPTGER4ELANELMNAMEN1 | |
| SCHEMBL8472117 | 0.85 | L3MBTL1 (0.46) | KDM4EPTGER4ELANELMNAMEN1 | |
| SCHEMBL8473765 | 0.84 | PTGER4 (0.52) | KDM4EPTGER4ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8472027 | 0.84 | L3MBTL1 (0.47) | KDM4EELANELMNAMEN1KMT2A | |
| SCHEMBL8477130 | 0.83 | KMT2A (0.55) | KDM4EPTGER4ELANELMNAMEN1 | |
| SCHEMBL8475515 | 0.83 | PTGER4 (0.51) | KDM4EPTGER4LMNAALDH1A1HSD17B10 | |
| SCHEMBL8476027 | 0.82 | KMT2A (0.52) | KDM4EPTGER4LMNAKMT2AALDH1A1 | |
| SCHEMBL8475123 | 0.82 | CNR1 (0.51) | PTGER4ALDH1A1CNR2 | |
| SCHEMBL8477133 | 0.81 | PTGER4 (0.48) | KDM4EPTGER4LMNAALDH1A1CNR2 | |
| SCHEMBL8474648 | 0.81 | PTGER4 (0.48) | KDM4EPTGER4LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |