SCHEMBL847218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL847925	0.88	TSHR (0.52)	PTH1RLMNATDP1TSHRALDH1A1
	SCHEMBL847703	0.82	NEK2 (0.52)	PTH1RTSHRALDH1A1MAPK1KMT2A
	SCHEMBL847912	0.80	PTH1R (0.44)	AKR1B1PTH1R
	SCHEMBL848776	0.78	MEN1 (0.51)	PTH1RLMNAALDH1A1KMT2AHPGD
	SCHEMBL849546	0.77	TSHR (0.52)	PTH1RLMNATSHRALDH1A1MAPK1
	SCHEMBL850014	0.77	PTH1R (0.65)	PTH1RLMNAALDH1A1CYP2D6CYP2C9
	SCHEMBL849645	0.76	MEN1 (0.51)	PTH1RLMNATSHRALDH1A1KMT2A
	SCHEMBL849883	0.76	PTH1R (0.52)	PTH1RLMNATSHRALDH1A1CYP1A2
	SCHEMBL13385961	0.76	PTH1R (0.52)	PTH1RHTT
	SCHEMBL846939	0.75	MEN1 (0.54)	PTH1RTSHRSMN1; SMN2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.