SCHEMBL847703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL847925	0.82	TSHR (0.52)	EPHX2PTH1RPOLBMEN1KMT2A
	SCHEMBL847218	0.82	L3MBTL1 (0.48)	EPHX2HPGDPTH1RPOLBKMT2A
	SCHEMBL847912	0.81	PTH1R (0.44)	NEK2PTH1R
	SCHEMBL847220	0.80	CALCRL (0.50)	PTH1RMEN1KMT2ATSHRALDH1A1
	SCHEMBL846939	0.78	MEN1 (0.54)	EPHX2PTH1RMEN1KMT2ATSHR
	SCHEMBL848776	0.77	MEN1 (0.51)	NEK2HPGDPTH1RMEN1KMT2A
	SCHEMBL13552099	0.77	PTH1R (0.48)	PTH1RMEN1KMT2ATSHR
	SCHEMBL849883	0.77	PTH1R (0.52)	NEK2HPGDPTH1RTSHRMAPK1
	SCHEMBL13385961	0.77	PTH1R (0.52)	NEK2PTH1R
	SCHEMBL847208	0.77	PTH1R (0.48)	PTH1RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.