Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473162 | 0.84 | TBXA2R (0.42) | TBXA2RKDM1AGAAMEN1KMT2A | |
| SCHEMBL8470780 | 0.84 | TBXA2R (0.42) | TBXA2RKDM1AMAPTALDH1A1LMNA | |
| SCHEMBL6968049 | 0.84 | TSHR (0.47) | TBXA2RKDM1A | |
| SCHEMBL6967844 | 0.78 | OPRM1 (0.42) | TBXA2RALDH1A1POLB | |
| SCHEMBL8471637 | 0.78 | OPRM1 (0.42) | TBXA2RALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8472080 | 0.75 | KDM1A (0.47) | TBXA2RKDM1AMAPTMEN1KMT2A | |
| SCHEMBL6973757 | 0.74 | TBXA2R (0.40) | TBXA2RKDM1A | |
| SCHEMBL8472698 | 0.74 | TBXA2R (0.36) | TBXA2RKDM1A | |
| SCHEMBL5448043 | 0.74 | TSHR (0.55) | TBXA2RKDM1AALDH1A1L3MBTL1HTR1A | |
| SCHEMBL6966660 | 0.73 | TSHR (0.40) | TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |