Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470780 | 0.88 | TBXA2R (0.42) | TBXA2RKDM1AOPRM1OPRD1OPRK1 | |
| SCHEMBL6968049 | 0.88 | TSHR (0.47) | TBXA2RKDM1AOPRM1TSHRNPSR1 | |
| SCHEMBL8472702 | 0.84 | TBXA2R (0.50) | TBXA2RKDM1AMEN1GAAKMT2A | |
| SCHEMBL6967844 | 0.81 | OPRM1 (0.42) | TBXA2ROPRM1OPRK1TSHRNPSR1 | |
| SCHEMBL8471637 | 0.81 | OPRM1 (0.42) | TBXA2ROPRM1OPRD1OPRK1TSHR | |
| SCHEMBL8472080 | 0.81 | KDM1A (0.47) | TBXA2RKDM1AADRB2MEN1KMT2A | |
| SCHEMBL6973757 | 0.78 | TBXA2R (0.40) | TBXA2RKDM1ATSHRNPSR1ADRB2 | |
| SCHEMBL6966660 | 0.77 | TSHR (0.40) | TBXA2ROPRM1OPRK1TSHRNPSR1 | |
| SCHEMBL6969520 | 0.77 | TBXA2R (0.39) | TBXA2RKDM1AOPRM1TSHRNPSR1 | |
| SCHEMBL8472751 | 0.76 | HDAC8 (0.42) | TBXA2RKDM1AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |