Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR1F | P30939 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472187 | 0.90 | MEN1 (0.62) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472591 | 0.86 | MEN1 (0.62) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL8472324 | 0.86 | MEN1 (0.53) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL8475163 | 0.85 | MEN1 (0.50) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8476135 | 0.85 | POLB (0.48) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472571 | 0.84 | DRD2 (0.52) | DRD2DRD3MEN1KMT2APOLB | |
| SCHEMBL19661278 | 0.84 | MEN1 (0.66) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL7616574 | 0.84 | KMT2A (0.52) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL8475171 | 0.82 | KDM4E (0.56) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL8472570 | 0.81 | MEN1 (0.44) | HTR6HTR1ADRD2DRD4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |