Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 5/20 | 0.63 |
| ▸ | BCHE | P06276 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208663 | 0.90 | HTT (0.74) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL8472225 | 0.87 | HTT (0.71) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL8476129 | 0.86 | HTT (0.73) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL8474173 | 0.85 | BCHE (0.66) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL9382159 | 0.84 | KDM4E (0.65) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL9748781 | 0.84 | KDM4E (0.68) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL9387187 | 0.83 | KDM4E (0.69) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL7945036 | 0.82 | BCHE (0.65) | ACHEBCHE | |
| SCHEMBL10061487 | 0.82 | HTT (0.67) | HTTGAAMAPTACHEBCHE | |
| SCHEMBL9384234 | 0.82 | KDM4E (0.72) | HTTGAAMAPTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861411-A | TREATING DISTURBANCES OF MEMORY SUCH AS SENILE DEMENTIA AND ALZHEIMER'S DISEASE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-01-19 | — | — | US | disclosed |