Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476671 | 0.91 | KMT2A (0.47) | KMT2AEGFRPTGER4MEN1 | |
| SCHEMBL8472891 | 0.90 | EGFR (0.45) | EGFRLTB4RLTB4R2ALOX5 | |
| SCHEMBL8476486 | 0.90 | PTGER4 (0.50) | KMT2APTGER4LMNAL3MBTL1MEN1 | |
| SCHEMBL8472573 | 0.89 | KMT2A (0.44) | KMT2APTGER4MEN1 | |
| SCHEMBL7609587 | 0.88 | KMT2A (0.46) | KMT2APTGER4LMNAMEN1 | |
| SCHEMBL8474896 | 0.87 | EGFR (0.47) | EGFRPTGER4L3MBTL1 | |
| SCHEMBL8479371 | 0.86 | PTGER4 (0.41) | KMT2APTGER4LMNAMEN1 | |
| SCHEMBL8472402 | 0.86 | PTGER4 (0.49) | KMT2APTGER4LMNAL3MBTL1MEN1 | |
| SCHEMBL8479051 | 0.86 | EGFR (0.41) | EGFRALOX5 | |
| SCHEMBL8472561 | 0.85 | HDAC3 (0.41) | KMT2AEGFRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |