Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475829 | 0.90 | PLA2G2A (0.42) | LTA4HMAPT | |
| SCHEMBL8479051 | 0.90 | EGFR (0.41) | EGFRLTA4HALOX5NPY5RMAOB | |
| SCHEMBL8473259 | 0.90 | KMT2A (0.45) | EGFRALOX5LTB4RLTB4R2 | |
| SCHEMBL8472561 | 0.88 | HDAC3 (0.41) | EGFRLTA4HALOX5NPY5R | |
| SCHEMBL8477366 | 0.88 | ALDH1A1 (0.47) | MAPT | |
| SCHEMBL7612724 | 0.87 | ALDH1A1 (0.39) | MAPT | |
| SCHEMBL8472046 | 0.85 | SLC6A5 (0.43) | MAOB | |
| SCHEMBL8472006 | 0.85 | HTT (0.52) | EGFRLTA4H | |
| SCHEMBL8898763 | 0.84 | TSPO (0.38) | LTB4RLTB4R2 | |
| SCHEMBL8473687 | 0.84 | LTA4H (0.44) | LTA4HNPY5RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |