SCHEMBL847379

SCHEMBL847379

CCCCOC(=O)CCCCCBr

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.70
DNM1 Q05193 1/20 0.58
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
NAAA Q02083 1/20 0.53
PAM P19021 2/20 0.53
FAAH O00519 1/20 0.53
HTR2C P28335 1/20 0.51
TSHR P16473 1/20 0.50
MAPT P10636 1/20 0.50
ALDH1A1 P00352 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1366913 1.00 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL1364973 1.00 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL1366455 1.00 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL1365023 0.98 DGKA (0.67) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25355680 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25191417 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25121055 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25342186 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25181489 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL24573011 0.94 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734989-A2 SYNTHESIS AND IN VITRO CHARACTERIZATION OF PROTEOLYSIS TARGETING CHIMERAS (PROTACS) FOR DEGRADATION OF DNA METHYLTRANSFERASE 1 (DNMT1) Dana-Farber Cancer Institute, Inc. (US) 2026-05-06 EP disclosed
WO-2025006902-A2 SYNTHESIS AND IN VITRO CHARACTERIZATION OF PROTEOLYSIS TARGETING CHIMERAS (PROTACS) FOR DEGRADATION OF DNA METHYLTRANSFERASE 1 (DNMT1) DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-01-02 WO disclosed
WO-2024154763-A1 LINKER FOR ANTIBODY-DRUG CONJUGATES, AND ANTIBODY-DRUG CONJUGATE 大塚製薬株式会社 2024-07-25 WO disclosed
EP-3731869-A1 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2020-11-04 EP disclosed
US-20130046087-A1 Substituted Cyclodextrin Derivatives Useful As Intermediates For Producing Biologically Active Materials ARCARIOS BV (NL) 2013-02-21 US disclosed
EP-2550299-A2 Substituted cyclodextrin derivatives and process for their preparation Arcarios B.V. (NL) 2013-01-30 EP disclosed
CN-102834416-A Substituted cyclodextrin derivatives useful as intermediates for producing biologically active materials ARCARIOS BV 2012-12-19 CN disclosed
EP-2432318-A1 BIMACROCYCLIC HCV NS3 PROTEASE INHIBITORS Sequoia Pharmaceuticals, Inc. (US) 2012-03-28 EP disclosed
US-8067136-B2 Charge control agent, toner, image forming method, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2011-11-29 US disclosed
WO-2011117317-A2 SUBSTITUTED CYCLODEXTRIN DERIVATIVES USEFUL AS INTERMEDIATES FOR PRODUCING BIOLOGICALLY ACTIVE MATERIALS ARCARIOS BV (NL) 2011-09-29 WO disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121204-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121207-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
CN-1072666-C (Azetidin-1-ylalkyl) lactams as tachykinin antagonists PFIZER RES AND DEV CO N V S A (IE) 2001-10-10 CN disclosed
CN-1154699-A (Azetidin-1-ylalkyl) lactams as tachykinin antagonists PFIZER LTD (IE) 1997-07-16 CN disclosed
EP-0313474-B1 AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
US-5075043-A Liquid crystals EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0370922-A2 An optical article containing a linear condensation polymer exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (US) 1990-05-30 EP disclosed
EP-0313474-A2 An optical article exhibiting a high level of second order polarization susceptibility EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-04-26 EP disclosed
US-4792208-A POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1988-12-20 US disclosed