SCHEMBL1365023

SCHEMBL1365023

CCCCOC(=O)CCCCBr

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.67
DNM1 Q05193 1/20 0.55
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
PAM P19021 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NAAA Q02083 1/20 0.50
FAAH O00519 1/20 0.50
HTR2C P28335 1/20 0.49
TSHR P16473 2/20 0.47
MAPT P10636 1/20 0.47
ATM Q13315 2/20 0.47
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
EPHX2 P34913 1/20 0.45
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1364973 0.98 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL847379 0.98 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL1366455 0.98 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL1366913 0.98 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL21811473 0.94 DGKA (0.70) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL321083 0.94 DGKA (0.63) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25191417 0.92 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL24588753 0.92 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL24573011 0.92 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3
SCHEMBL25121055 0.92 DGKA (0.74) DGKADNM1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638678-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-12-03 EP disclosed
EP-4036079-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-11-19 EP disclosed
US-12396961-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2025-08-26 US disclosed
EP-3394030-B2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-02-12 EP disclosed
US-12077501-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2024-09-03 US disclosed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
EP-4212522-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H Biotech Inc. (KR) 2023-07-19 EP disclosed
EP-4036079-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS ModernaTX, Inc. (US) 2022-08-03 EP disclosed
US-20070117937-A1 Polyhydroxyalkanoic acid having ester, carboxyl or sulfonic acid group and producing method thereor CANON KABUSHIKI KAISHA (JP) 2007-05-24 US disclosed
EP-1774410-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2007-04-18 EP disclosed
US-20070073006-A1 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group, and sulfonic group, and method of producing the same CANON KABUSHIKI KAISHA (JP) 2007-03-29 US disclosed
EP-1758948-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR Canon Kabushiki Kaisha (JP) 2007-03-07 EP disclosed
US-20060194071-A1 Developer carrying member and development apparatus CANON KABUSHIKI KAISHA (JP) 2006-08-31 US disclosed
US-20050287484-A1 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2005-12-29 US disclosed
WO-2005121204-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121205-A2 POLYHYDROXYALKANOATE HAVING ESTER GROUP, CABOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121208-A1 POLYHYDROXYALKANOIC ACID HAVING ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF EGFR, KRAS, ERBB2 DGKA 824/4885DNM1 2988/4885PRSS1 987/4885
US-12396961-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 DGKA 271/4885DNM1 1160/4885PRSS1 2594/4885
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA DGKA 2032/4885DNM1 4250/4885PRSS1 938/4885
US-12077501-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 DGKA 271/4885DNM1 1160/4885PRSS1 2594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.