Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478641 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL6169842 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1SLC40A1HTR6KIT | |
| SCHEMBL8475048 | 0.85 | PTGS2 (0.41) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8478256 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8473864 | 0.84 | PTGS1 (0.42) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8477499 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8478783 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8474198 | 0.82 | PTGS2 (0.41) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8480051 | 0.82 | PTGS1 (0.45) | PTGS2PTGS1SLC40A1HTR6SCN9A | |
| SCHEMBL8478741 | 0.82 | PTGS2 (0.40) | PTGS2PTGS1SLC40A1HTR6SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |