Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.56 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
| ▸ | GABRE | P78334 | 1/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472864 | 0.78 | HTR1B (0.64) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8979737 | 0.77 | HTR6 (0.58) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29206564 | 0.76 | HTR6 (0.67) | HTR6SLC6A4 | |
| SCHEMBL7375886 | 0.76 | HTR6 (0.67) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8506646 | 0.76 | HTR6 (0.67) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30877187 | 0.76 | HTR6 (0.67) | HTR6SLC6A4 | |
| SCHEMBL7375881 | 0.76 | HTR6 (0.67) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8506642 | 0.76 | HTR6 (0.67) | HTR6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL12244098 | 0.76 | HTR6 (0.67) | HTR6HTR1AHTR1BHTR2CHTR1F | |
| SCHEMBL8610962 | 0.76 | HTR6 (0.67) | HTR6GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886008-A | 5-arylindole derivatives | PFIZER INC. (US) | 1999-03-23 | — | — | US | claimed |
| US-5886008-A | 5-arylindole derivatives | PFIZER INC. (US) | 1999-03-23 | — | — | US | disclosed |