Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479336 | 0.87 | GCGR (0.31) | GCGR | |
| SCHEMBL8481067 | 0.85 | GCGR (0.33) | TSHRGCGRALDH1A1HPGDHSD17B10 | |
| SCHEMBL8480091 | 0.82 | PTGS2 (0.47) | GAAMAPK1 | |
| SCHEMBL8477832 | 0.81 | TP53 (0.34) | PDCD1CD274GCGRALDH1A1HPGD | |
| SCHEMBL8479563 | 0.77 | CYP4F2 (0.42) | TDP1HPGDGAAMAPK1 | |
| SCHEMBL8479432 | 0.75 | GCGR (0.41) | TDP1GCGRALDH1A1HPGDHSD17B10 | |
| SCHEMBL8477304 | 0.74 | PDCD1 (0.38) | TDP1PDCD1CD274TSHRGCGR | |
| SCHEMBL8476215 | 0.74 | PDE4B (0.42) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8481471 | 0.74 | PDE4B (0.46) | TDP1ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8481612 | 0.73 | MAPT (0.35) | ALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |