Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474110 | 0.87 | GCGR (0.35) | PDCD1CD274GCGRALDH1A1HSD17B10 | |
| SCHEMBL8476959 | 0.83 | PDCD1 (0.36) | PDCD1CD274PTGS1GCGRALDH1A1 | |
| SCHEMBL8475295 | 0.82 | PTGS2 (0.44) | ESR2GAAMEN1KMT2ABACE1 | |
| SCHEMBL8477677 | 0.80 | PDE4B (0.43) | TDP1ALDH1A1GAABACE1PDE4B | |
| SCHEMBL8480921 | 0.75 | PDCD1 (0.36) | PDCD1CD274PTGS1ALDH1A1HPGD | |
| SCHEMBL8474276 | 0.74 | TDP1 (0.34) | PDCD1CD274TDP1GCGRALDH1A1 | |
| SCHEMBL8476218 | 0.74 | GCGR (0.33) | GCGRALDH1A1GAA | |
| SCHEMBL8477928 | 0.74 | PTGS2 (0.38) | PDCD1CD274PTGS1ALDH1A1PDE4B | |
| SCHEMBL8474594 | 0.73 | RHEB (0.35) | TDP1ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL22129263 | 0.73 | PTGS1 (0.35) | PDCD1CD274PTGS1GCGRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |