Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511995 | 0.83 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL30447171 | 0.83 | LMNA (0.41) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL30447644 | 0.83 | LMNA (0.41) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL19114984 | 0.83 | LMNA (0.41) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL30447284 | 0.83 | LMNA (0.41) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL10917780 | 0.79 | LMNA (0.43) | LMNADNM1FDPSGPR84SPHK1 | |
| SCHEMBL9077222 | 0.79 | LMNA (0.43) | LMNADNM1CA2FDPSGPR84 | |
| SCHEMBL27342880 | 0.78 | FDPS (0.45) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL11671819 | 0.77 | LMNA (0.37) | LMNADNM1TSHRTHRBCA2 | |
| SCHEMBL3037635 | 0.77 | LMNA (0.37) | LMNADNM1TSHRTHRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880235-A | POLYMER PREPARED BY COPOLYMERIZING ALPHA-METHYLENE-GAMMA-BUTYROLACTONE AND VINYLICALLY UNSATURATED MONOMER | AGOMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-09 | — | — | US | disclosed |
| US-4100057-A | WITH MORPHOLINE, METAL PHTHALOCYANINE CATALYST | UOP INC. (US) | 1978-07-11 | — | — | US | disclosed |