SCHEMBL8474353

SCHEMBL8474353

CCc1ccc(-c2c([O])cc(F)c(CCc3cc(F)c(C(F)(F)F)c(F)c3)c2F)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470997 0.92 DAO (0.35) DAO
SCHEMBL8473755 0.90 DAO (0.34) DAO
SCHEMBL8471090 0.89 ESR1 (0.33)
SCHEMBL8475369 0.89 RARB (0.37) DAO
SCHEMBL8472473 0.87 FFAR4 (0.38) DAO
SCHEMBL8474710 0.85 DAO (0.39) DAO
SCHEMBL8472687 0.85 FFAR4 (0.32)
SCHEMBL8475071 0.83 TRPV4 (0.31)
SCHEMBL8471263 0.81 DAO (0.36) DAO
SCHEMBL8472717 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed