Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473158 | 0.92 | ALDH1A1 (0.41) | PDE9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8470743 | 0.90 | TSHR (0.37) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL8470570 | 0.89 | TSHR (0.41) | MEN1ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL8836445 | 0.88 | FFAR4 (0.34) | FFAR4 | |
| SCHEMBL8475071 | 0.87 | TRPV4 (0.31) | PDE9ATRPV4 | |
| SCHEMBL8836518 | 0.87 | DAO (0.41) | TRPV4 | |
| SCHEMBL8472567 | 0.87 | CYP2A6 (0.45) | PDE9ACYP2A6GRIA2GRIA4FFAR4 | |
| SCHEMBL8475221 | 0.87 | TRPV4 (0.31) | TRPV4 | |
| SCHEMBL8472473 | 0.82 | FFAR4 (0.38) | FFAR4 | |
| SCHEMBL8470863 | 0.82 | TRPV4 (0.31) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |