Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3562943 | 0.81 | TDP1 (0.53) | TDP1ALDH1A1P2RY1GAAMAPT | |
| SCHEMBL2878935 | 0.76 | TDP1 (0.54) | TDP1ALDH1A1P2RY1GAAMAPT | |
| SCHEMBL239798 | 0.75 | KDM4E (0.58) | TDP1ALDH1A1P2RY1GAAMAPT | |
| SCHEMBL8009202 | 0.74 | KMT2A (0.65) | TDP1ALDH1A1P2RY1KMT2AKDM4E | |
| SCHEMBL4938450 | 0.73 | TDP1 (0.51) | TDP1ALDH1A1P2RY1GAAMAPT | |
| SCHEMBL243134 | 0.72 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPTMAPK8KMT2A | |
| SCHEMBL10807074 | 0.72 | TDP1 (0.50) | TDP1ALDH1A1P2RY1MAPK8KMT2A | |
| SCHEMBL15924716 | 0.72 | MAPK8 (0.52) | TDP1ALDH1A1GAAMAPK8KMT2A | |
| SCHEMBL13005228 | 0.72 | PDE10A (0.51) | TDP1ALDH1A1MAPTMAPK8KMT2A | |
| SCHEMBL11183197 | 0.72 | TDP1 (0.50) | TDP1ALDH1A1MAPTMAPK8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977146-A | Pyridylcarbamates, process and intermediates for their preparation, and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0874825-A1 | PYRIDYL CARBAMATES, PROCESS AND INTERMEDIATES FOR THE PREPARATION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997021679-A1 | PYRIDYL CARBAMATES, PROCESS AND INTERMEDIATES FOR THE PREPARATION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-19 | — | — | WO | disclosed |