Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SLC40A1 | Q9NP59 | 10/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424512 | 0.80 | P2RY1 (0.63) | CCR2P2RY1 | |
| SCHEMBL3102839 | 0.79 | KDM4E (0.63) | KMT2AALDH1A1POLBL3MBTL1SLC40A1 | |
| SCHEMBL1569119 | 0.78 | L3MBTL1 (0.79) | KMT2AALDH1A1POLBL3MBTL1SLC40A1 | |
| SCHEMBL8626115 | 0.76 | TUBB4A (0.65) | KMT2AALDH1A1POLBL3MBTL1SLC40A1 | |
| SCHEMBL17570175 | 0.76 | SLC40A1 (0.78) | KMT2APOLBSLC40A1GLO1G6PD | |
| SCHEMBL21084781 | 0.75 | SLC40A1 (0.63) | KMT2AALDH1A1SLC40A1GLO1G6PD | |
| SCHEMBL28946370 | 0.75 | MEN1 (0.83) | KMT2ASLC40A1GLO1G6PDNFKBIA | |
| SCHEMBL3113839 | 0.75 | KMT2A (0.77) | KMT2AALDH1A1POLBL3MBTL1SLC40A1 | |
| SCHEMBL8474603 | 0.74 | TDP1 (0.54) | KMT2AALDH1A1L3MBTL1TDP1KDM4E | |
| SCHEMBL850835 | 0.73 | ST14 (0.75) | KMT2AALDH1A1POLBL3MBTL1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000047209-A1 | METHODS OF MODULATING URIC ACID LEVELS | TULARIK INC. (US) | 2000-08-17 | — | — | WO | claimed |
| WO-2000047209-A1 | METHODS OF MODULATING URIC ACID LEVELS | TULARIK INC. (US) | 2000-08-17 | — | — | WO | disclosed |