Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.50 |
| ▸ | CHUK | O15111 | 4/20 | 0.48 |
| ▸ | ICOSLG | O75144 | 3/20 | 0.48 |
| ▸ | ICOS | Q9Y6W8 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28460754 | 0.78 | MCHR1 (0.61) | MCHR1MAPT | |
| SCHEMBL7447526 | 0.77 | NISCH (0.47) | MAOAMCHR1PARP1MAPT | |
| SCHEMBL16377295 | 0.70 | PARP1 (0.76) | ROCK2CHUKPARP1CSNK2A1DYRK1A | |
| SCHEMBL14054138 | 0.70 | KIF11 (0.51) | CHUKMAOAMAPTDYRK1A | |
| SCHEMBL7445054 | 0.69 | MCHR1 (0.49) | MCHR1MAPT | |
| Hydrochloric Acid SCHEMBL7437697 | 0.68 | MCHR1 (0.48) | MCHR1MAPT | |
| SCHEMBL17520087 | 0.67 | CHUK (0.56) | CHUKMAOAMAPTDYRK1A | |
| SCHEMBL17783431 | 0.67 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL16377113 | 0.67 | PARP1 (0.74) | ROCK2CHUKMAOAPARP1CSNK2A1 | |
| SCHEMBL8324250 | 0.66 | MAPT (0.53) | ROCK2MCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990107-A | ADMINISTERING TO INHIBIT THE BINDING OF FIBRINOGEN TO BLOOD PLATELETS IN A MAMMAL; OR TO INHIBIT OSTEOCLAST MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1999-11-23 | — | — | US | disclosed |