Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.37 |
| ▸ | HTR2A | P28223 | 10/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473037 | 0.84 | DRD2 (0.54) | DRD2HTR2AHTR1ASLC6A4HTR7 | |
| SCHEMBL8471209 | 0.84 | HTR1D (0.39) | DRD2HTR2AHTR1ASLC6A4HTR7 | |
| SCHEMBL6773788 | 0.78 | ADRA1D (0.41) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL8471473 | 0.78 | HTR2A (0.41) | HTR2AHTR7 | |
| SCHEMBL8476361 | 0.75 | CYP1A2 (0.37) | DRD2HTR2AHTR1A | |
| SCHEMBL8471130 | 0.75 | DRD2 (0.50) | DRD2HTR2AHTR1ASLC6A4HTR7 | |
| SCHEMBL8472362 | 0.74 | DRD2 (0.54) | DRD2HTR2AHTR1ASLC6A4HTR7 | |
| SCHEMBL8477450 | 0.74 | DRD2 (0.36) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL10395172 | 0.72 | DRD2 (0.62) | DRD2HTR2ASLC6A4 | |
| SCHEMBL8471031 | 0.71 | DRD2 (0.53) | DRD2HTR2ASLC6A4HTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962448-A | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |