SCHEMBL8475310

SCHEMBL8475310

CN1CCC1C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 11/20 0.56
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TSHR P16473 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP2C19 P33261 1/20 0.48
PREP P48147 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13099455 0.91 FKBP1A (0.60) FKBP1ATSHRPREP
SCHEMBL26291061 0.91 FKBP1A (0.60) FKBP1ATSHRPREP
SCHEMBL12869918 0.91 FKBP1A (0.60) FKBP1ATSHRPREP
SCHEMBL24710613 0.89 FKBP1A (0.65) FKBP1A
SCHEMBL22019554 0.82 FKBP1A (0.48) FKBP1ASMN1; SMN2NPC1RAB9ATSHR
SCHEMBL29180237 0.82 FKBP1A (0.51) FKBP1ASMN1; SMN2NPC1RAB9ATSHR
SCHEMBL29072821 0.82 HTR2C (0.50) FKBP1ASMN1; SMN2NPC1RAB9ATSHR
SCHEMBL28431477 0.82 FKBP1A (0.60) FKBP1ASMN1; SMN2NPC1RAB9ACYP2C19
SCHEMBL27848121 0.81 TSHR (0.49) FKBP1ASMN1; SMN2NPC1RAB9ATSHR
SCHEMBL631581 0.81 FKBP1A (0.58) FKBP1ASMN1; SMN2NPC1RAB9ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed