Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642808 | 0.83 | PREP (0.53) | FKBP1APREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8475310 | 0.82 | FKBP1A (0.56) | FKBP1APREPALDH1A1NPC1RAB9A | |
| SCHEMBL26291061 | 0.80 | FKBP1A (0.60) | FKBP1APREPTSHR | |
| SCHEMBL13099455 | 0.80 | FKBP1A (0.60) | FKBP1APREPTSHR | |
| SCHEMBL12869918 | 0.80 | FKBP1A (0.60) | FKBP1APREPTSHR | |
| SCHEMBL24710613 | 0.77 | FKBP1A (0.65) | FKBP1A | |
| SCHEMBL11311747 | 0.76 | PREP (0.54) | PREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29072821 | 0.76 | HTR2C (0.50) | FKBP1AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25590373 | 0.76 | PREP (0.47) | FKBP1APREPALDH1A1TSHR | |
| SCHEMBL8923967 | 0.74 | POLB (0.49) | FKBP1AALDH1A1TSHRHTR2CFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157085-A1 | MODULATORS OF HEMOGLOBIN | GLOBAL BLOOD THERAPEUTICS, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157085-A1 | MODULATORS OF HEMOGLOBIN | HBG1, HBG2, HBB | FKBP1A 1300/4885PREP 840/4885ALDH1A1 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.