Terephthalic Acid

Terephthalic Acid

SCHEMBL8475377

C=Cc1ccccc1.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
ALDH1A1 P00352 2/20 0.64
DAO P14920 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
TP53 P04637 1/20 0.55
SRD5A2 P31213 2/20 0.54
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
TRPA1 O75762 1/20 0.48
TRIM24 O15164 1/20 0.47
TRIM33 Q9UPN9 1/20 0.47
KMT2A Q03164 2/20 0.47
AKT1 P31749 1/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
TYR P14679 1/20 0.46
DRD1 P21728 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3804735 0.98 ALDH1A1 (0.61) TSHRALDH1A1DAONAPRTCA1
Benzoic Acid SCHEMBL385226 0.95 ALDH1A1 (0.64) TSHRALDH1A1DAONAPRTCA1
Benzene SCHEMBL7535464 0.93 ALDH1A1 (0.60) TSHRALDH1A1DAONAPRTCA1
Terephthalic Acid SCHEMBL27955569 0.92 TSHR (0.54) TSHRALDH1A1DAONAPRTCA1
SCHEMBL16536 0.91 ALDH1A1 (0.62) TSHRALDH1A1DAONAPRTCA1
Terephthalic Acid SCHEMBL6270577 0.90 UNG (0.56) TSHRALDH1A1DAONAPRTCA1
SCHEMBL8490138 0.88 ALDH1A1 (0.60) TSHRALDH1A1DAONAPRTCA1
SCHEMBL9742687 0.88 ALDH1A1 (0.60) TSHRALDH1A1DAONAPRTCA1
SCHEMBL11050679 0.88 ALDH1A1 (0.60) TSHRALDH1A1DAONAPRTCA1
Bromide SCHEMBL3627952 0.88 ALDH1A1 (0.60) TSHRALDH1A1DAONAPRTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111787846-A Tool for use with an image capture device to capture quality images and method thereof 宝洁公司 2020-10-16 CN claimed
CN-109873163-A Current collector, pole piece and battery thereof and application 宁德时代新能源科技股份有限公司 2019-06-11 CN claimed
CN-108281662-A Current collector, pole piece and battery thereof and application 宁德时代新能源科技股份有限公司 2018-07-13 CN claimed
CN-113773558-B PLA (polylactic acid), PBAT (poly (butylene adipate terephthalate) and ST (styrene terephthalate)) degradable composite material and production process thereof 浙江绿禾生态科技股份有限公司 2022-11-18 CN disclosed
CN-113773558-B PLA (polylactic acid), PBAT (poly (butylene adipate terephthalate) and ST (styrene terephthalate)) degradable composite material and production process thereof 浙江绿禾生态科技股份有限公司 2022-11-18 CN disclosed
CN-113773558-A PLA (polylactic acid), PBAT (poly (butylene adipate terephthalate) and ST (styrene terephthalate)) degradable composite material and production process thereof 浙江绿禾生态科技股份有限公司 2021-12-10 CN disclosed
CN-113773558-A PLA (polylactic acid), PBAT (poly (butylene adipate terephthalate) and ST (styrene terephthalate)) degradable composite material and production process thereof 浙江绿禾生态科技股份有限公司 2021-12-10 CN disclosed
WO-2021039364-A1 HOT-MELT ADHESIVE SHEET 日東シンコー株式会社 2021-03-04 WO disclosed
CN-111787846-A Tool for use with an image capture device to capture quality images and method thereof 宝洁公司 2020-10-16 CN disclosed
CN-111094381-A Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2020-05-01 CN disclosed
CN-111094380-A Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2020-05-01 CN disclosed
CN-104144800-B Tire 株式会社普利司通 2016-09-21 CN disclosed
CN-101201896-B Image pickup module for biometric authentication, biometric authentication device, and prism HITACHI MAXELL 2013-03-20 CN disclosed
CN-101201896-A Image pickup module for biometric authentication, biometric authentication device, and prism HITACHI MAXELL (JP) 2008-06-18 CN disclosed
CN-1788202-A Sheet-like probe, process for producing the same and its application JSR CORP (JP) 2006-06-14 CN disclosed
WO-1999048567-A1 PROCESS AND COMPOSITION FOR MAKING MULTI-LAYER GOLF BALLS USING RIGID UNCROSSLINKED SHELLS ACUSHNET COMPANY (US) 1999-09-30 WO disclosed