Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL8475377 | 0.95 | TSHR (0.64) | ALDH1A1TSHRDAONAPRTCES2 | |
| Styrene SCHEMBL3804735 | 0.93 | ALDH1A1 (0.61) | ALDH1A1TSHRDAONAPRTCES2 | |
| Terephthalic Acid SCHEMBL6270577 | 0.90 | UNG (0.56) | ALDH1A1TSHRDAONAPRTCES2 | |
| Isophthalic Acid SCHEMBL28305860 | 0.90 | UNG (0.60) | ALDH1A1TSHRDAONAPRTAKT1 | |
| Benzene SCHEMBL7535464 | 0.88 | ALDH1A1 (0.60) | ALDH1A1TSHRDAONAPRTCES2 | |
| 4-Vinylphenol SCHEMBL3118949 | 0.88 | CA2 (0.56) | ALDH1A1TSHRDAONAPRTCES2 | |
| Terephthalic Acid SCHEMBL27955569 | 0.88 | TSHR (0.54) | ALDH1A1TSHRDAONAPRTCES2 | |
| Benzophenone SCHEMBL28767057 | 0.86 | ALDH1A1 (0.64) | ALDH1A1TSHRDAONAPRTCES2 | |
| Benzil SCHEMBL5013455 | 0.86 | CES2 (0.64) | ALDH1A1TSHRDAONAPRTCES2 | |
| Benzoic Acid SCHEMBL28958549 | 0.86 | TSHR (0.52) | ALDH1A1TSHRDAONAPRTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106190275-A | A kind of used oil prepares the method for clean fuel liquid | 汝州鑫源生物能源科技有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-8101700-B2 | Phosphonic polymers having a phosphinate backbone and methods of making and using thereof | UNICHEM TECHNOLOGIES, INC. (US) | 2012-01-24 | — | — | US | claimed |
| US-20100168361-A1 | PHOSPHONIC POLYMERS HAVING A PHOSPHINATE BACKBONE AND METHODS OF MAKING AND USING THEREOF | UNICHEM TECHNOLOGIES, INC. (US) | 2010-07-01 | — | — | US | claimed |
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | SUNTRUST BANK | 2009-01-01 | — | — | US | claimed |
| US-5071953-A | Dissolving in solvent, applying to substrate, desolventizing by evaporation | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-12-10 | — | — | US | claimed |
| CN-115947761-B | Ruthenium carbene catalyst, composition containing ruthenium carbene catalyst, preparation method and application of ruthenium carbene catalyst | 上海中化科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-119708924-A | Ink, ink preparation method and ink-jet printing method | 广东聚华印刷显示技术有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-118834333-A | Modified acrylic resin and preparation method thereof | 重庆市化工研究院有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118459734-A | Conductive polymer material and application thereof in secondary battery | 蓝固(常州)新能源有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-117402322-A | Environment-friendly epoxy vinyl ester resin and preparation method and application thereof | 上海沪亨新材料科技股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-113583472-B | Modified pigment and preparation method and application thereof | 珠海传美讯新材料股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-111925453-B | Ecological cationic surface sizing reinforcing agent for papermaking and preparation method thereof | 浙江理工大学 | 2022-11-29 | — | — | CN | disclosed |
| WO-2005069998-A2 | NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME | BRIGHAM YOUNG UNIVERSITY TECHNOLOGY TRANSFER OFFICE (US) | 2005-08-04 | — | — | WO | disclosed |
| US-6617023-B2 | Splittable multi-component fiber, method for producing it, and fibrous article comprising it | CHISSO CORPORATION (JP) | 2003-09-09 | — | — | US | disclosed |
| US-20030039832-A1 | Splittable multi-component fiber, method for producing it, and fibrous article comprising it | CHISSO CORPORATION | 2003-02-27 | — | — | US | disclosed |
| US-6410139-B1 | Split type conjugate fiber, method for producing the same and fiber formed article using the same | CHISSO CORPORATION (JP) | 2002-06-25 | — | — | US | disclosed |
| CN-1057101-C | Reduction of polymerization inhibitor in recycle streams | FINA TECHNOLOGY (US) | 2000-10-04 | — | — | CN | disclosed |
| US-5741837-A | CONTAINING HYDROXYBENZIMIDAZOLE OR DIPHENYLALKYL HALIDE NUCLEATING AGENT | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1998-04-21 | — | — | US | disclosed |
| CN-1065868-A | Reduce the polymerization retarder in the cycling stream | FINA TACHNOLOGY INC (US) | 1992-11-04 | — | — | CN | disclosed |
| US-4197132-A | Photopolymer photoresist composition containing rosin tackifier adhesion improver and chlorinated polyolefin | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | PHOSPHO1, PPIP5K2, FASN | ALDH1A1 3501/4885TSHR 4765/4885DAO 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.