Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | PPARD | Q03181 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 4/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192443 | 0.84 | CTSK (0.73) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL7192447 | 0.84 | CTSK (0.73) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL8146131 | 0.77 | CTSK (0.50) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL7188131 | 0.76 | CTSK (0.71) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL7188134 | 0.76 | CTSK (0.71) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL25560675 | 0.73 | PPARG (0.78) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL25560799 | 0.73 | PPARG (0.78) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL29389477 | 0.72 | PPARG (1.00) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL10039861 | 0.72 | PPARG (1.00) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL28699738 | 0.72 | MAOB (0.62) | PPARGPPARDPPARADNMT1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045247-A1 | Compounds for the inhibition of histone deacetylase | NatureWise Biotech & Medicals Corporation (TW) | 2009-04-08 | — | — | EP | disclosed |