Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192447 | 0.84 | CTSK (0.73) | CTSKBCHEPPARGPPARAPPARD | |
| SCHEMBL7192443 | 0.84 | CTSK (0.73) | CTSKBCHEPPARGPPARAPPARD | |
| SCHEMBL8146133 | 0.80 | APP (0.49) | CTSKBCHEPPARGPPARAPPARD | |
| SCHEMBL8475453 | 0.77 | PPARG (0.56) | CTSKPPARGPPARAPPARDDNMT1 | |
| SCHEMBL23896921 | 0.74 | MAOB (0.57) | CTSKBCHEPPARGPPARAAPP | |
| SCHEMBL4261466 | 0.72 | APP (0.53) | PPARGPPARAPPARDDNMT1SIRT5 | |
| SCHEMBL5820932 | 0.70 | APP (0.52) | BCHEPPARGPPARAPPARDDNMT1 | |
| SCHEMBL5868933 | 0.69 | ACHE (0.56) | CTSKBCHEPPARGPPARABACE1 | |
| SCHEMBL5868935 | 0.69 | ACHE (0.56) | CTSKBCHEPPARGPPARABACE1 | |
| SCHEMBL7188134 | 0.69 | CTSK (0.71) | CTSKBCHEPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |