Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475130 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HTTCNR2PTGER4 | |
| Hydrochloric Acid SCHEMBL8475905 | 0.90 | UTS2R (0.39) | KDM4EALDH1A1HTTPTGER4TOP2A | |
| Hydrochloric Acid SCHEMBL8472661 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1HTTCNR2PTGER4 | |
| SCHEMBL7615052 | 0.87 | KDM4E (0.39) | KDM4EALDH1A1HTTCNR2PTGER4 | |
| SCHEMBL8472303 | 0.86 | POLB (0.43) | KDM4EALDH1A1PTGER4TOP2APOLB | |
| SCHEMBL8475096 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL7613036 | 0.86 | KDM4E (0.38) | KDM4EALDH1A1HTTCNR2PTGER4 | |
| SCHEMBL8477129 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1HTTCNR2TOP2A | |
| SCHEMBL8477495 | 0.85 | CNR2 (0.43) | KDM4EALDH1A1HTTCNR2TOP2A | |
| SCHEMBL8479051 | 0.84 | EGFR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |