Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477495 | 0.97 | CNR2 (0.43) | KDM4EALDH1A1HTTCNR2CHRM2 | |
| SCHEMBL8475130 | 0.94 | KDM4E (0.44) | KDM4EALDH1A1HTTCNR2HTR6 | |
| Hydrochloric Acid SCHEMBL8472661 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1HTTCNR2HTR6 | |
| SCHEMBL8474419 | 0.87 | CHRM2 (0.46) | KDM4EALDH1A1CNR2CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL8475905 | 0.86 | UTS2R (0.39) | KDM4EALDH1A1HTTHTR6POLB | |
| SCHEMBL8475477 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HTTCNR2HTR6 | |
| SCHEMBL8472569 | 0.86 | DNM1 (0.43) | KDM4ECNR2POLBTDP1CYP2D6 | |
| SCHEMBL8475096 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HTTHRH3POLB | |
| SCHEMBL8472860 | 0.84 | HTR7 (0.43) | KDM4EALDH1A1HTTCNR2POLB | |
| SCHEMBL8898545 | 0.84 | CNR2 (0.44) | KDM4EALDH1A1HTTCNR2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |