Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8472661 | 0.94 | KDM4E (0.42) | KDM4EALDH1A1HTTTSHRHTR6 | |
| SCHEMBL8477129 | 0.94 | KDM4E (0.43) | KDM4EALDH1A1HTTHTR6POLB | |
| SCHEMBL8477495 | 0.93 | CNR2 (0.43) | KDM4EALDH1A1HTTHTR6POLB | |
| Hydrochloric Acid SCHEMBL8475905 | 0.92 | UTS2R (0.39) | KDM4EALDH1A1HTTTSHRHTR6 | |
| SCHEMBL8475477 | 0.92 | KDM4E (0.39) | KDM4EALDH1A1HTTTSHRHTR6 | |
| SCHEMBL8475096 | 0.92 | KDM4E (0.39) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL8479051 | 0.90 | EGFR (0.41) | — | |
| Hydrochloric Acid SCHEMBL8474469 | 0.90 | ALDH1A1 (0.42) | KDM4EALDH1A1HTTTSHRHTR6 | |
| SCHEMBL7615052 | 0.89 | KDM4E (0.39) | KDM4EALDH1A1HTTTSHRHTR6 | |
| Hydrochloric Acid SCHEMBL8475839 | 0.88 | PTGER4 (0.44) | KDM4EALDH1A1HTTTSHRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |