Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377527 | 0.84 | PABPC1 (0.52) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL7947907 | 0.84 | PABPC1 (0.52) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL29265547 | 0.84 | PABPC1 (0.52) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL27533084 | 0.83 | UTS2R (0.38) | PABPC1APOBEC3AAPOBEC3GALDH1A1HPGD | |
| SCHEMBL11643170 | 0.83 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL8772074 | 0.83 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL28346760 | 0.83 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL8772060 | 0.83 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL10615626 | 0.83 | ALDH1A1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 | |
| SCHEMBL28346759 | 0.83 | PABPC1 (0.51) | PABPC1APOBEC3AAPOBEC3GALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004954-A | TREATING GRAFT-VERSUS-HOST DISEASE AND AUTOIMMUNE DISEASES; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-21 | — | — | US | disclosed |