Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480525 | 0.91 | MGAM (0.42) | CYP4F2CYP4A11MGAMGAASI | |
| SCHEMBL8474577 | 0.89 | MGAM (0.46) | CYP4F2CYP4A11MGAMGAASI | |
| SCHEMBL8476879 | 0.88 | GAA (0.40) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL8474999 | 0.85 | GAA (0.41) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL8478958 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL8476983 | 0.81 | GAA (0.40) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL8474594 | 0.81 | RHEB (0.35) | CYP4F2CYP4A11LTA4HTDP1GSTP1 | |
| SCHEMBL8474291 | 0.79 | MGAM (0.43) | MGAMGAASIMGAM2GSTP1 | |
| SCHEMBL8477816 | 0.79 | GAA (0.43) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL8475454 | 0.78 | GAA (0.41) | MGAMGAASIMGAM2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |