Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SI | P14410 | 4/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474291 | 0.91 | MGAM (0.43) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL8475781 | 0.89 | CYP4F2 (0.41) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL8480525 | 0.88 | MGAM (0.42) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL8475330 | 0.88 | MGAM (0.45) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL8475444 | 0.85 | LTA4H (0.41) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL8478292 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2NPSR1 | |
| SCHEMBL8478958 | 0.83 | MGAM (0.46) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL8476879 | 0.81 | GAA (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL8476983 | 0.79 | GAA (0.40) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL8474999 | 0.78 | GAA (0.41) | MGAMGAASIMGAM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |