Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476879 | 0.93 | GAA (0.40) | GAAMGAMSIMGAM2GSTP1 | |
| SCHEMBL8480525 | 0.91 | MGAM (0.42) | GAAMGAMSIMGAM2NPC1 | |
| SCHEMBL8475454 | 0.90 | GAA (0.41) | GAAMGAMSIMGAM2NPC1 | |
| SCHEMBL8474291 | 0.88 | MGAM (0.43) | GAAMGAMSIMGAM2HTT | |
| SCHEMBL8480887 | 0.84 | GAA (0.43) | GAAMGAMSIMGAM2NPC1 | |
| SCHEMBL8474999 | 0.82 | GAA (0.41) | GAAMGAMSIMGAM2GSTP1 | |
| SCHEMBL8474261 | 0.82 | MGAM (0.42) | GAAMGAMSIMGAM2NPC1 | |
| SCHEMBL8475781 | 0.81 | CYP4F2 (0.41) | GAAMGAMSIMGAM2GSTP1 | |
| SCHEMBL8474577 | 0.79 | MGAM (0.46) | GAAMGAMSIMGAM2HTT | |
| SCHEMBL8475330 | 0.79 | MGAM (0.45) | GAAMGAMSIMGAM2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |