Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934173 | 1.00 | PTGS2 (0.70) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL8933918 | 0.96 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8933922 | 0.96 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8933829 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL14747810 | 0.76 | PTGS2 (0.55) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL14747608 | 0.76 | PTGS2 (0.55) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL6349332 | 0.70 | LMNA (0.41) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL6349331 | 0.70 | LMNA (0.41) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL14747816 | 0.70 | LMNA (0.41) | PTGS2PTGS1LMNAGAA | |
| SCHEMBL5698663 | 0.70 | PTGS2 (0.82) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | claimed |
| US-5886016-A | ANTIINFLAMMATORY AGENT WITH MINIMAL SIDE EFFECTS FOR TREATING ARTHRITIS | G.D. SEARLE & CO. (US) | 1999-03-23 | — | — | US | disclosed |
| WO-1996009304-A1 | BENZOPYRANOPYRAZOLYL DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-28 | — | — | WO | disclosed |