Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MYLK | Q15746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286894 | 0.76 | PKM (0.56) | HTR6CYP3A4KMT2AMEN1CYP1A2 | |
| SCHEMBL8476811 | 0.75 | HRH4 (0.60) | MAPK14 | |
| SCHEMBL7450856 | 0.74 | CYP3A4 (0.58) | HTR6MAPK1CYP3A4NFKB1KMT2A | |
| SCHEMBL4936109 | 0.70 | USP2 (0.57) | MAPTUSP2PKMKDR | |
| SCHEMBL6421791 | 0.70 | USP2 (0.57) | MAPTUSP2PKM | |
| Hydrochloric Acid SCHEMBL6728400 | 0.69 | USP2 (0.56) | MAPTUSP2PKMKDR | |
| SCHEMBL16026638 | 0.69 | MAPT (0.59) | HTR6MAPK1CYP3A4NFKB1KMT2A | |
| SCHEMBL7450870 | 0.68 | TDO2 (0.56) | HTR6MAPK1CYP3A4NFKB1KMT2A | |
| SCHEMBL30610303 | 0.68 | USP2 (0.66) | HTR6MAPK1CYP3A4NFKB1KMT2A | |
| SCHEMBL654111 | 0.68 | USP2 (0.66) | HTR6MAPK1CYP3A4NFKB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |